Hair loss in men

Alopecia, commonly called baldness, is another of the manifestations of the aging process, whose most frequent cause is the so-called androgenic alopecia, which affects almost half of men between 18 and 40 years old, and in the case of older than 70 years, the percentage rises to 95%. (Piraccini & Alessandrini, 2014). It is such a frequent process that it can almost be considered a normal physiological event. Its manifestations are:

  • A lot of hair is lost when washed.
  • Hair becomes thinner, dull and brittle.
  • Hair falls out when brushed.
  • There is more hair on the pillow.
  • Lower density and volume of hair.
  • The hair entries are increasingly broad.
  • There are areas of baldness in the crown.
  • The scalp is seen more easily through the hair.
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Causes of Alopecia

  • Androgenic alopecia (the most frequent).
  • Trauma (accidents, burns, etc.).
  • Radiation (nuclear accidents, radiotherapy, etc.).
  • Surgeries (surgical scars).
  • Medications (cancer chemotherapy and other drugs).
  • Chemicals (by exposure).
  • Nutritional alterations (nutritional deficiencies).
  • Hormonal alterations (thyroid, androgenic diseases, etc.).
  • Systemic and localized diseases (discoid lupus, lichen planus, alopecia areata, folliculitis decalvans, hypothyroidism, nutritional deficiencies, among others).
  • Efluvium: this is the name given to the event of greater hair loss compared to the usual fall, due to the fact that a greater number of follicles enter the telogen phase or fall phase, caused by various factors, whether hormonal, seasonal (for example, the spring effluvium or autumnal effluvium) or otherwise.

Classification Androgenic Alopecia

Today it is known that, in the vast majority of cases, alopecia is caused by the effect of Dihydrotestosterone or DHT, which is a natural metabolite that occurs when the enzyme called 5-alpha-reductase acts on the hormone called testosterone. Testosterone and DHT occur naturally in both men and women, although in much larger amounts in the male gender.

In androgenic alopecia, DHT acts on the hair follicles through different biochemical signals, causing an increase in the sebaceous gland, a decrease in the size of the follicle and the hair that it produces, with the consequent progressive miniaturization of the hair until its definitive fall. The hair follicle finally sclerose and stops producing hair.

Baldness is a progressive process that in each person is presented at a different speed. In men, the sequence of the fall usually begins in the parietal areas (entries), and later in the medial or frontoparietal area. Hair loss in the vertex (crown) can occur in the early stages of baldness or in later stages.

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Progression Androgenic Alopecia

The Norwood-Hamilton classification is the most used; in this you can see the progression experienced by most male patients.

Both patterns, Standard and Pattern A, can evolve to Norwood VI and VII.

DIAGNOSIS

– Advanced trichoscopic analysis with high resolution microscopic images.

– Laboratory tests that may include: specific hormonal profiles, blood profiles, nutritional profiles, etc.

Treatment for Alopecia in Men

Alopecia in men requires in the first instance an accurate diagnosis about the cause and thus to establish an appropriate specific treatment, either a topical pharmacological treatment (for example, a lotion to apply) or a medicine taken orally, or perhaps treatment is required Surgical by a follicular unit transplant or the combination of these.

A new and revolutionary treatment strategy is the use of stem cells, a treatment that increases the quality of the hair follicle and therefore the thickness of the hair and its density. In addition, stem cells provide advantages with respect to the treatments that were available so far:

  • It can be used as preventive treatment, before hair loss is very advanced and visible (for example, in people who have family members who have experienced baldness at an early age).
  • It can be used to revitalize hair follicles of hair that have lost their shine, strength and vitality.
  • It can be used in conjunction with other treatments, surprisingly improving the results of hair transplants.
  • The application is done only once and does not need maintenance or daily applications.

Our patients who have received baldness treatment with stem cells have shown surprising results. This therapy will surely position itself as the fundamental treatment against hair loss and the prevention of hair loss.

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